| 1. Journée | 21.08.2020 | Shakhtar Donetsk | - | Kolos Kovalivka | 3:1 |  |
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| 2. Journée | 12.09.2020 | Kolos Kovalivka | - | FK Lviv | 4:0 | |
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| 6. Journée | 17.10.2020 | Zorya Lugansk | - | Kolos Kovalivka | 1:1 | ||||
| 7. Journée | 25.10.2020 | Kolos Kovalivka | - | FC Mynai | 2:2 | ||||
| 8. Journée | 31.10.2020 | Kolos Kovalivka | - | Olimpik Donetsk | 1:2 | |
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| 10. Journée | 22.11.2020 | Vorskla Poltava | - | Kolos Kovalivka | 3:0 | ||||
| 11. Journée | 29.11.2020 | Kolos Kovalivka | - | Desna Chernigov | 1:1 | ||||
| 13. Journée | 12.12.2020 | Dinamo Kiev | - | Kolos Kovalivka | 2:2 | ||||
| 14. Journée | 14.02.2021 | Kolos Kovalivka | - | Shakhtar Donetsk | 0:0 | ||||
| 15. Journée | 20.02.2021 | FK Lviv | - | Kolos Kovalivka | 0:2 | ||||
| 16. Journée | 27.02.2021 | Kolos Kovalivka | - | Rukh Lviv | 1:2 | |
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| 18. Journée | 14.03.2021 | FK Mariupol | - | Kolos Kovalivka | 1:4 | ||||
| 19. Journée | 21.03.2021 | Kolos Kovalivka | - | Zorya Lugansk | 1:0 | ||||
| 23. Journée | 24.04.2021 | Kolos Kovalivka | - | Vorskla Poltava | 3:0 | ||||
| 24. Journée | 01.05.2021 | Desna Chernigov | - | Kolos Kovalivka | 2:2 | ||||
| 25. Journée | 05.05.2021 | FK Oleksandriya | - | Kolos Kovalivka | 0:2 | ||||
| 26. Journée | 09.05.2021 | Kolos Kovalivka | - | Dinamo Kiev | 0:3 |
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