| 2. Journée | 22.02.2022 | Deportes Temuco | - | Santiago Wanderers | 1:0 | ||||
| 3. Journée | 02.03.2022 | Santiago Wanderers | - | Santiago Morning | 2:2 | ||||
| 5. Journée | 17.03.2022 | Santiago Wanderers | - | Rangers | 1:3 | ||||
| 18. Journée | 02.07.2022 | Deportes Iquique | - | Santiago Wanderers | 2:1 | ||||
| 22. Journée | 02.08.2022 | Rangers | - | Santiago Wanderers | 1:2 | ||||
| 24. Journée | 12.08.2022 | CD Magallanes | - | Santiago Wanderers | 0:1 |  |
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| 19. Journée | 17.08.2022 | Santiago Wanderers | - | Deportes Temuco | 3:0 | ||||
| 25. Journée | 21.08.2022 | Santiago Wanderers | - | Deportes Copiapó | 1:0 | ||||
| 26. Journée | 28.08.2022 | Puerto Montt | - | Santiago Wanderers | 1:1 | ||||
| 27. Journée | 06.09.2022 | Santiago Wanderers | - | Deportes Melipilla | 2:2 | ||||
| 28. Journée | 10.09.2022 | Unión San Felipe | - | Santiago Wanderers | 2:3 | ||||
| 29. Journée | 25.09.2022 | Santiago Wanderers | - | Recoleta | 0:0 | ||||
| 30. Journée | 03.10.2022 | Barnechea | - | Santiago Wanderers | 1:0 |
Chili