| 1. Journée | 10.02.2022 | Newell's Old Boys II | - | Defensa y Justicia II | 2:0 | ||||
| 2. Journée | 15.02.2022 | Argentinos Juniors II | - | Newell's Old Boys II | 1:1 | ||||
| 3. Journée | 19.02.2022 | Newell's Old Boys II | - | River Plate II | 1:2 | ||||
| 4. Journée | 24.02.2022 | Talleres de Córdoba II | - | Newell's Old Boys II | 2:2 | ||||
| 5. Journée | 04.03.2022 | Newell's Old Boys II | - | Atlético Tucumán II | 2:3 | ||||
| 6. Journée | 10.03.2022 | Sarmiento de Junín II | - | Newell's Old Boys II | 1:2 | ||||
| 7. Journée | 18.03.2022 | Rosario Central II | - | Newell's Old Boys II | 2:1 |
Argentine