| 18. Journée | 13.02.2021 | HNK Orijent Rijeka | - | NK Osijek II | 3:0 | ||||
| 19. Journée | 22.02.2021 | NK Osijek II | - | Hrvatski Dragovoljac | 0:0 | ||||
| 20. Journée | 28.02.2021 | NK Croatia Zmijavci | - | NK Osijek II | 1:0 | ||||
| 21. Journée | 06.03.2021 | NK Junak Sinj | - | NK Osijek II | 1:1 | ||||
| 22. Journée | 13.03.2021 | NK Osijek II | - | NK Dugopolje | 2:0 | ||||
| 23. Journée | 19.03.2021 | NK Međimurje | - | NK Osijek II | 0:1 |  |
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| 24. Journée | 02.04.2021 | NK Osijek II | - | NK Inter Zaprešić | 1:2 | ||||
| 26. Journée | 17.04.2021 | NK Osijek II | - | NK Opatija | 1:0 |  |
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| 28. Journée | 24.04.2021 | NK Osijek II | - | NK BSK Bijelo Brdo | 3:0 | ||||
| 27. Journée | 28.04.2021 | Dinamo Zagreb II | - | NK Osijek II | 3:0 | ||||
| 29. Journée | 02.05.2021 | Hajduk Split II | - | NK Osijek II | 4:3 | ||||
| 33. Journée | 22.05.2021 | HNK Cibalia | - | NK Osijek II | 2:2 |
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