| 7. Journée | 26.08.1980 | RC Strasbourg | - | AS Monaco | 0:0 | ||||
| 8. Journée | 29.08.1980 | AS Monaco | - | US Valenciennes-Anzin | 5:1 | ||||
| 9. Journée | 09.09.1980 | AJ Auxerre | - | AS Monaco | 0:0 | ||||
| 10. Journée | 12.09.1980 | FC Metz | - | AS Monaco | 1:1 | ||||
| 12. Journée | 26.09.1980 | Stade Lavallois | - | AS Monaco | 3:3 | ||||
| 13. Journée | 04.10.1980 | AS Monaco | - | FC Sochaux | 2:1 | ||||
| 16. Journée | 31.10.1980 | Nîmes Olympique | - | AS Monaco | 1:3 | ||||
| 18. Journée | 12.11.1980 | Girondins Bordeaux | - | AS Monaco | 1:0 | ||||
| 19. Journée | 23.11.1980 | AS Monaco | - | OGC Nice | 1:0 | ||||
| 20. Journée | 29.11.1980 | Lille OSC | - | AS Monaco | 2:1 | ||||
| 21. Journée | 07.12.1980 | AS Monaco | - | Olympique Lyonnais | 2:1 | ||||
| 22. Journée | 13.12.1980 | Angers SCO | - | AS Monaco | 1:1 | ||||
| 23. Journée | 20.12.1980 | AS Monaco | - | SC Bastia | 3:0 | ||||
| 26. Journée | 08.02.1981 | US Valenciennes-Anzin | - | AS Monaco | 0:1 | ||||
| 28. Journée | 28.02.1981 | AS Monaco | - | FC Metz | 2:1 | ||||
| 32. Journée | 15.04.1981 | AS Monaco | - | RC Lens | 1:0 | ||||
| 37. Journée | 29.05.1981 | OGC Nice | - | AS Monaco | 2:1 |
France