| 4. Journée | 24.02.2022 | River Plate II | - | Racing Club II | 4:2 | ||||
| 5. Journée | 04.03.2022 | San Lorenzo II | - | River Plate II | 0:4 | ||||
| 6. Journée | 10.03.2022 | River Plate II | - | Gimnasia de La Plata II | 2:4 | ||||
| 10. Journée | 14.04.2022 | Banfield II | - | River Plate II | 2:3 | ||||
| 11. Journée | 20.04.2022 | Talleres de Córdoba II | - | River Plate II | 1:1 | ||||
| 12. Journée | 25.04.2022 | River Plate II | - | Atlético Tucumán II | 4:0 | ||||
| 13. Journée | 29.04.2022 | Sarmiento de Junín II | - | River Plate II | 1:2 | ||||
| 14. Journée | 05.05.2022 | River Plate II | - | Platense II | 2:2 |
Argentine