| 3. Journée | 29.01.2021 | Boston River | - | Cerro Largo | 2:1 | ||||
| 4. Journée | 04.02.2021 | Montevideo Wanderers | - | Boston River | 2:2 | ||||
| 5. Journée | 07.02.2021 | Boston River | - | Peñarol | 1:2 | ||||
| 6. Journée | 11.02.2021 | River Plate | - | Boston River | 3:1 |  |
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| 9. Journée | 23.02.2021 | Boston River | - | Progreso | 2:3 | ||||
| 13. Journée | 19.03.2021 | Boston River | - | Danubio | 1:5 |
Uruguay
Italie