| 1. Journée | 12.08.2021 | Balzan FC | - | Sliema Wanderers | 1:0 | ||||
| 2. Journée | 20.08.2021 | Sliema Wanderers | - | Floriana FC | 0:0 | ||||
| 3. Journée | 11.09.2021 | Gżira United | - | Sliema Wanderers | 1:1 |  |
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| 4. Journée | 19.09.2021 | Sliema Wanderers | - | Gudja United | 2:3 | ||||
| 5. Journée | 26.09.2021 | Sirens FC | - | Sliema Wanderers | 2:2 | ||||
| 6. Journée | 17.10.2021 | Sliema Wanderers | - | Hibernians FC | 0:3 | ||||
| 7. Journée | 24.10.2021 | St. Luċija FC | - | Sliema Wanderers | 0:0 |
Cameroun