| 1. Journée | 08.08.2010 | River Plate | - | Tigre | 1:0 | ||||
| 2. Journée | 15.08.2010 | Huracán | - | River Plate | 0:1 |  |
|||
| 3. Journée | 22.08.2010 | River Plate | - | Independiente | 3:2 |  |
|||
| 4. Journée | 29.08.2010 | Argentinos Juniors | - | River Plate | 0:0 | ||||
| 5. Journée | 06.09.2010 | Vélez Sarsfield | - | River Plate | 2:1 | ||||
| 6. Journée | 12.09.2010 | River Plate | - | Arsenal de Sarandí | 1:0 | ||||
| 7. Journée | 19.09.2010 | Newell's Old Boys | - | River Plate | 1:0 | ||||
| 8. Journée | 27.09.2010 | River Plate | - | Quilmes | 1:1 | ||||
| 9. Journée | 04.10.2010 | Banfield | - | River Plate | 2:2 | |
|||
| 10. Journée | 11.10.2010 | River Plate | - | Gimnasia de La Plata | 0:0 | ||||
| 11. Journée | 18.10.2010 | Godoy Cruz | - | River Plate | 2:2 | ||||
| 12. Journée | 23.10.2010 | River Plate | - | Racing Club | 1:1 | ||||
| 13. Journée | 07.11.2010 | All Boys | - | River Plate | 1:0 | ||||
| 14. Journée | 16.11.2010 | River Plate | - | Boca Juniors | 1:0 | |
|||
| 15. Journée | 21.11.2010 | San Lorenzo | - | River Plate | 0:0 | |
|||
| 16. Journée | 28.11.2010 | River Plate | - | Olimpo de Bahía Blanca | 1:0 | ||||
| 17. Journée | 05.12.2010 | Colón de Santa Fe | - | River Plate | 1:2 | ||||
| 18. Journée | 08.12.2010 | River Plate | - | Estudiantes | 0:4 | |
Argentine