| 1. Journée | 04.02.2022 | Universidad Cesar Vallejo | - | Cienciano | 0:0 |  |
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| 2. Journée | 13.02.2022 | Cienciano | - | Deportivo Municipal | 4:2 | |
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| 3. Journée | 21.02.2022 | Cienciano | - | AD Tarma | 0:0 | ||||
| 4. Journée | 26.02.2022 | Deportivo Binacional | - | Cienciano | 3:2 | |
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| 6. Journée | 13.03.2022 | Universitario de Deportes | - | Cienciano | 1:1 | |
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| 7. Journée | 19.03.2022 | Cienciano | - | Sport Boys | 4:1 | ||||
| 8. Journée | 03.04.2022 | Atlético Grau | - | Cienciano | 1:2 |  |
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| 10. Journée | 16.04.2022 | Mannucci | - | Cienciano | 0:2 | |
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| 11. Journée | 23.04.2022 | Cienciano | - | Sporting Cristal | 0:1 | |
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| 14. Journée | 16.05.2022 | Sport Huancayo | - | Cienciano | 3:3 | ||||
| 15. Journée | 21.05.2022 | Cienciano | - | Universidad Técnica | 3:2 | ||||
| 16. Journée | 31.05.2022 | Alianza Lima | - | Cienciano | 1:0 | |
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| 17. Journée | 18.06.2022 | Cienciano | - | Academia Cantolao | 1:0 | |
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| 18. Journée | 26.06.2022 | Carlos Stein | - | Cienciano | 2:2 |
Pérou