| 15. Journée | 06.10.2022 | Club Olimpia | - | Tacuary | 1:0 |  |
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| 16. Journée | 12.10.2022 | Tacuary | - | General Caballero DJLM | 0:3 | ||||
| 17. Journée | 15.10.2022 | Resistencia SC | - | Tacuary | 0:3 | ||||
| 18. Journée | 22.10.2022 | Tacuary | - | 12 de Octubre de Itauguá | 5:1 | ||||
| 19. Journée | 26.10.2022 | Sol de América | - | Tacuary | 2:2 | ||||
| 20. Journée | 31.10.2022 | Tacuary | - | Club Nacional | 2:1 | ||||
| 21. Journée | 06.11.2022 | Guaraní | - | Tacuary | 2:1 | ||||
| 22. Journée | 12.11.2022 | Tacuary | - | Libertad | 1:0 |
Paraguay