| 1er tour | 15.09.2005 | AS Roma | - | Aris Saloniki | 5:1 |  |
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| 1er tour | 29.09.2005 | Aris Saloniki | - | AS Roma | 0:0 | ||||
| Groupe E | 20.10.2005 | Tromsø IL | - | AS Roma | 1:2 | |
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| Groupe E | 24.11.2005 | AS Roma | - | RC Strasbourg | 1:1 | ||||
| 3e tour | 15.02.2006 | Club Brugge KV | - | AS Roma | 1:2 | |
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| tour des 16 | 09.03.2006 | Middlesbrough FC | - | AS Roma | 1:0 | ||||
| tour des 16 | 15.03.2006 | AS Roma | - | Middlesbrough FC | 2:1 |
France