| 1. Journée | 05.02.2022 | Montevideo City Torque | - | Cerro Largo | 1:1 | ||||
| 3. Journée | 19.02.2022 | Defensor Sporting | - | Montevideo City Torque | 1:3 |  |
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| 4. Journée | 28.02.2022 | Montevideo City Torque | - | Albion | 1:2 | |
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| 5. Journée | 13.03.2022 | Nacional | - | Montevideo City Torque | 1:1 | |
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| 6. Journée | 22.03.2022 | Montevideo City Torque | - | Danubio | 1:1 | ||||
| 7. Journée | 04.04.2022 | Deportivo Maldonado | - | Montevideo City Torque | 2:1 | ||||
| 8. Journée | 12.04.2022 | Montevideo City Torque | - | Rentistas | 2:0 | |
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| 9. Journée | 16.04.2022 | Liverpool | - | Montevideo City Torque | 2:0 | ||||
| 10. Journée | 24.04.2022 | Montevideo City Torque | - | Peñarol | 0:1 | ||||
| 11. Journée | 07.05.2022 | Cerrito | - | Montevideo City Torque | 2:2 | ||||
| 12. Journée | 15.05.2022 | Montevideo Wanderers | - | Montevideo City Torque | 1:1 |  |
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| 14. Journée | 28.05.2022 | Boston River | - | Montevideo City Torque | 3:1 |
Uruguay