| 1. Journée | 17.07.2010 | Tacuary | - | Club Rubio Ñu | 0:0 |  |
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| 3. Journée | 31.07.2010 | Tacuary | - | 3 de Febrero | 2:0 | ||||
| 4. Journée | 07.08.2010 | Guaraní | - | Tacuary | 1:0 | ||||
| 5. Journée | 15.08.2010 | Tacuary | - | Cerro Porteño | 0:1 | |
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| 6. Journée | 21.08.2010 | Sport Colombia | - | Tacuary | 1:3 | ||||
| 7. Journée | 28.08.2010 | Tacuary | - | Sol de América | 1:1 | ||||
| 8. Journée | 05.09.2010 | Sportivo Trinidense | - | Tacuary | 1:1 | ||||
| 9. Journée | 11.09.2010 | Tacuary | - | Sportivo Luqueño | 0:3 | ||||
| 10. Journée | 19.09.2010 | Tacuary | - | Club Olimpia | 1:4 | ||||
| 12. Journée | 02.10.2010 | Club Rubio Ñu | - | Tacuary | 1:2 |  |
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| 14. Journée | 16.10.2010 | 3 de Febrero | - | Tacuary | 0:0 | ||||
| 15. Journée | 21.10.2010 | Tacuary | - | Guaraní | 1:1 | ||||
| 16. Journée | 24.10.2010 | Cerro Porteño | - | Tacuary | 1:3 | ||||
| 17. Journée | 30.10.2010 | Tacuary | - | Sport Colombia | 2:1 | |
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| 18. Journée | 06.11.2010 | Sol de América | - | Tacuary | 0:1 | |
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| 19. Journée | 13.11.2010 | Tacuary | - | Sportivo Trinidense | 0:1 | ||||
| 20. Journée | 21.11.2010 | Sportivo Luqueño | - | Tacuary | 3:1 | ||||
| 21. Journée | 27.11.2010 | Club Olimpia | - | Tacuary | 2:1 | |
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| 22. Journée | 03.12.2010 | Tacuary | - | Club Nacional | 1:2 |
Paraguay