| 5. Journée | 20.03.2021 | Mushuc Runa | - | Macará | 0:0 | ||||
| 6. Journée | 03.04.2021 | LDU Quito | - | Mushuc Runa | 0:0 | ||||
| 7. Journée | 08.04.2021 | Mushuc Runa | - | Olmedo | 4:0 |  |
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| 8. Journée | 12.04.2021 | Orense SC | - | Mushuc Runa | 0:2 | ||||
| 9. Journée | 17.04.2021 | Mushuc Runa | - | Barcelona | 2:2 | ||||
| 13. Journée | 23.05.2021 | Mushuc Runa | - | Emelec | 1:2 | |
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| 14. Journée | 29.05.2021 | Guayaquil City | - | Mushuc Runa | 0:0 | ||||
| 15. Journée | 17.07.2021 | Mushuc Runa | - | Delfín SC | 6:1 |  |
Colombie