| 1. Journée | 05.02.2017 | Defensor Sporting | - | Rampla Juniors | 1:0 |  |
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| 2. Journée | 11.02.2017 | Defensor Sporting | - | CA Cerro | 1:1 | |
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| 3. Journée | 19.02.2017 | Sud América | - | Defensor Sporting | 1:2 | |
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| 4. Journée | 25.02.2017 | Defensor Sporting | - | Juventud de Las Piedras | 2:1 | |
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| 5. Journée | 05.03.2017 | Danubio | - | Defensor Sporting | 0:2 | ||||
| 6. Journée | 12.03.2017 | Defensor Sporting | - | Plaza Colonia | 1:3 | ||||
| 7. Journée | 19.03.2017 | River Plate | - | Defensor Sporting | 0:1 |  |
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| 9. Journée | 02.04.2017 | Racing | - | Defensor Sporting | 0:0 | |
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| 10. Journée | 08.04.2017 | Defensor Sporting | - | El Tanque Sisley | 3:0 | |
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| 11. Journée | 16.04.2017 | Liverpool | - | Defensor Sporting | 0:1 | ||||
| 12. Journée | 23.04.2017 | Defensor Sporting | - | Boston River | 1:0 | |
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| 13. Journée | 30.04.2017 | Montevideo Wanderers | - | Defensor Sporting | 2:3 | |
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| 14. Journée | 06.05.2017 | Defensor Sporting | - | Nacional | 3:2 | |
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| 15. Journée | 13.05.2017 | Fénix | - | Defensor Sporting | 1:2 |
Uruguay