| 10. Journée | 24.10.2021 | NK Osijek II | - | NK Varaždin | 0:0 | ||||
| 12. Journée | 07.11.2021 | NK Osijek II | - | NK Rudeš | 2:1 | ||||
| 11. Journée | 12.11.2021 | NK Inter Zaprešić | - | NK Osijek II | 2:0 | ||||
| 13. Journée | 19.11.2021 | NK Kustošija | - | NK Osijek II | 0:0 | ||||
| 14. Journée | 27.11.2021 | NK Osijek II | - | NK Jarun | 0:0 |  |
|||
| 15. Journée | 05.12.2021 | NK BSK Bijelo Brdo | - | NK Osijek II | 0:2 | ||||
| 16. Journée | 12.02.2022 | NK Osijek II | - | NK Sesvete | 0:3 | ||||
| 17. Journée | 20.02.2022 | Dinamo Zagreb II | - | NK Osijek II | 2:1 | |
|||
| 18. Journée | 26.02.2022 | NK Osijek II | - | NK Dugopolje | 2:0 | ||||
| 19. Journée | 05.03.2022 | NK Solin | - | NK Osijek II | 0:0 | ||||
| 20. Journée | 14.03.2022 | NK Osijek II | - | NK Dubrava | 0:1 | ||||
| 21. Journée | 20.03.2022 | NK Croatia Zmijavci | - | NK Osijek II | 1:0 | |
|||
| 23. Journée | 09.04.2022 | NK Opatija | - | NK Osijek II | 1:2 | ||||
| 24. Journée | 15.04.2022 | NK Osijek II | - | HNK Cibalia | 2:1 | ||||
| 25. Journée | 23.04.2022 | NK Varaždin | - | NK Osijek II | 4:1 | ||||
| 27. Journée | 07.05.2022 | NK Rudeš | - | NK Osijek II | 1:0 | ||||
| 29. Journée | 21.05.2022 | NK Jarun | - | NK Osijek II | 3:0 |
Autriche