| 1er tour | 06.07.2021 | Mosta FC | - | Spartak Trnava | 3:2 |  |
|||
| 1er tour | 15.07.2021 | Spartak Trnava | - | Mosta FC | 2:0 | ||||
| 2e tour | 22.07.2021 | Spartak Trnava | - | Sepsi OSK | 0:0 | ||||
| 2e tour | 29.07.2021 | Sepsi OSK | - | Spartak Trnava | 3:4 tab | ||||
| 3e tour | 05.08.2021 | Spartak Trnava | - | Maccabi Tel Aviv | 0:0 | ||||
| 3e tour | 12.08.2021 | Maccabi Tel Aviv | - | Spartak Trnava | 1:0 |
Slovaquie