| 2. Journée | 18.09.2021 | Cerrito | - | Cerro Largo | 1:1 | ||||
| 4. Journée | 02.10.2021 | River Plate | - | Cerro Largo | 0:4 | ||||
| 6. Journée | 17.10.2021 | Cerro Largo | - | Progreso | 1:0 | ||||
| 7. Journée | 21.10.2021 | Sud América | - | Cerro Largo | 0:0 | ||||
| 8. Journée | 25.10.2021 | Cerro Largo | - | Plaza Colonia | 1:0 |  |
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| 9. Journée | 31.10.2021 | Fénix | - | Cerro Largo | 1:4 | ||||
| 10. Journée | 04.11.2021 | Cerro Largo | - | Boston River | 1:1 | ||||
| 12. Journée | 15.11.2021 | Cerro Largo | - | Rentistas | 1:1 | ||||
| 15. Journée | 05.12.2021 | Villa Española | - | Cerro Largo | 1:1 |
Uruguay
Italie