| 1. Journée | 30.07.2000 | Estudiantes | - | River Plate | 1:1 | ||||
| 2. Journée | 06.08.2000 | River Plate | - | Vélez Sarsfield | 2:1 | ||||
| 3. Journée | 19.08.2000 | Colón de Santa Fe | - | River Plate | 1:2 | ||||
| 4. Journée | 27.08.2000 | River Plate | - | Rosario Central | 4:1 | ||||
| 5. Journée | 06.09.2000 | Independiente | - | River Plate | 0:1 | ||||
| 6. Journée | 10.09.2000 | River Plate | - | Talleres de Córdoba | 4:1 | ||||
| 7. Journée | 17.09.2000 | CA Los Andes | - | River Plate | 0:4 |  |
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| 8. Journée | 24.09.2000 | River Plate | - | San Lorenzo | 2:2 | ||||
| 9. Journée | 01.10.2000 | Chacarita Juniors | - | River Plate | 1:0 | ||||
| 10. Journée | 15.10.2000 | River Plate | - | Boca Juniors | 1:1 | ||||
| 11. Journée | 22.10.2000 | Argentinos Juniors | - | River Plate | 2:2 | |
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| 12. Journée | 27.10.2000 | River Plate | - | Unión de Santa Fe | 1:1 | |
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| 13. Journée | 05.11.2000 | Gimnasia de La Plata | - | River Plate | 2:2 | |
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| 15. Journée | 19.11.2000 | Racing Club | - | River Plate | 0:1 | ||||
| 16. Journée | 26.11.2000 | River Plate | - | Belgrano de Córdoba | 4:2 | ||||
| 17. Journée | 03.12.2000 | Almagro | - | River Plate | 4:5 | |
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| 18. Journée | 10.12.2000 | River Plate | - | Huracán | 1:1 | ||||
| 19. Journée | 17.12.2000 | Lanús | - | River Plate | 3:2 | |
Colombie