| 2. Journée | 16.01.2022 | Deportivo Saprissa | - | AD San Carlos | 1:2 |  |
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| 3. Journée | 22.01.2022 | AD San Carlos | - | Municipal Pérez Zeledón | 1:1 | ||||
| 4. Journée | 04.02.2022 | Guadalupe | - | AD San Carlos | 3:1 |  |
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| 5. Journée | 11.02.2022 | AD San Carlos | - | CS Herediano | 1:1 | ||||
| 6. Journée | 15.02.2022 | AD San Carlos | - | AD Guanacasteca | 3:1 | ||||
| 7. Journée | 19.02.2022 | Municipal Grecia | - | AD San Carlos | 0:1 | |
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| 8. Journée | 26.02.2022 | AD San Carlos | - | Jicaral | 1:1 | ||||
| 12. Journée | 06.04.2022 | Santos de Guápiles | - | AD San Carlos | 1:1 | |
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| 13. Journée | 10.04.2022 | AD San Carlos | - | Deportivo Saprissa | 4:1 | |
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| 14. Journée | 14.04.2022 | Municipal Pérez Zeledón | - | AD San Carlos | 1:0 | ||||
| 15. Journée | 20.04.2022 | AD San Carlos | - | Guadalupe | 2:1 | ||||
| 16. Journée | 24.04.2022 | CS Herediano | - | AD San Carlos | 1:1 | ||||
| 17. Journée | 27.04.2022 | AD Guanacasteca | - | AD San Carlos | 2:3 | |
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| 18. Journée | 01.05.2022 | AD San Carlos | - | Municipal Grecia | 2:2 | |
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| 20. Journée | 09.05.2022 | AD San Carlos | - | CS Cartaginés | 3:2 |  |
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| 22. Journée | 15.05.2022 | AD San Carlos | - | Sporting FC | 2:1 |
Costa Rica