| Groupe E | 15.09.2010 | Bayern München | - | AS Roma | 2:0 | ||||
| Groupe E | 28.09.2010 | AS Roma | - | CFR Cluj | 2:1 | ||||
| Groupe E | 19.10.2010 | AS Roma | - | FC Basel 1893 | 1:3 |  |
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| Groupe E | 03.11.2010 | FC Basel 1893 | - | AS Roma | 2:3 | |
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| Groupe E | 23.11.2010 | AS Roma | - | Bayern München | 3:2 | ||||
| Groupe E | 08.12.2010 | CFR Cluj | - | AS Roma | 1:1 | ||||
| tour des 16 | 16.02.2011 | AS Roma | - | Shakhtar Donetsk | 2:3 | |
Italie