| 2. Journée | 14.03.2021 | Atlético Palmaflor | - | Real Santa Cruz | 1:0 | ||||
| 1. Journée | 28.03.2021 | Real Santa Cruz | - | Jorge Wilstermann | 0:2 | ||||
| 4. Journée | 09.04.2021 | Royal Pari | - | Real Santa Cruz | 3:2 | ||||
| 6. Journée | 02.05.2021 | CD Guabirá | - | Real Santa Cruz | 1:0 |  |
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| 7. Journée | 07.05.2021 | Real Santa Cruz | - | Blooming | 1:0 | |
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| 5. Journée | 12.05.2021 | Real Santa Cruz | - | Real Potosí | 4:1 |
Argentine