| Quarts de finale | 25.11.2021 | CF Monterrey | - | Atlas Guadalajara | 0:0 |  |
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| Quarts de finale | 28.11.2021 | Atlas Guadalajara | - | CF Monterrey | 1:1 | ||||
| Demi-finales | 03.12.2021 | Pumas UNAM | - | Atlas Guadalajara | 0:1 | ||||
| Demi-finales | 06.12.2021 | Atlas Guadalajara | - | Pumas UNAM | 0:1 | ||||
| Finale | 10.12.2021 | Club León | - | Atlas Guadalajara | 3:2 |  |
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| Finale | 13.12.2021 | Atlas Guadalajara | - | Club León | 4:3 tab | |
Mexique