| Ligaphase | 25.09.2024 | Manchester United | - | FC Twente | 1:1 | ||||
| Ligaphase | 03.10.2024 | FC Twente | - | Fenerbahçe | 1:1 | ||||
| Ligaphase | 24.10.2024 | FC Twente | - | Lazio Roma | 0:2 |  |
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| Ligaphase | 28.11.2024 | FC Twente | - | Union Saint-Gilloise | 0:1 | ||||
| Ligaphase | 12.12.2024 | Olympiakos Piraeus | - | FC Twente | 0:0 | ||||
| Ligaphase | 23.01.2025 | Malmö FF | - | FC Twente | 2:3 | ||||
| Ligaphase | 30.01.2025 | FC Twente | - | Beşiktaş | 1:0 | ||||
| Play-offs | 13.02.2025 | FC Twente | - | FK Bodø/Glimt | 2:1 | ||||
| Play-offs | 20.02.2025 | FK Bodø/Glimt | - | FC Twente | 5:2 ap |
Allemagne