| 3. Journée | 19.02.2022 | Newell's Old Boys II | - | River Plate II | 1:2 |  |
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| 4. Journée | 24.02.2022 | Talleres de Córdoba II | - | Newell's Old Boys II | 2:2 | ||||
| 5. Journée | 04.03.2022 | Newell's Old Boys II | - | Atlético Tucumán II | 2:3 | ||||
| 6. Journée | 10.03.2022 | Sarmiento de Junín II | - | Newell's Old Boys II | 1:2 | ||||
| 9. Journée | 08.04.2022 | Unión de Santa Fe II | - | Newell's Old Boys II | 1:1 | ||||
| 10. Journée | 13.04.2022 | Newell's Old Boys II | - | Patronato de Paraná II | 1:0 |
Argentine