| 2. Journée | 20.01.2021 | River Plate | - | CA Cerro | 1:2 |  |
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| 4. Journée | 04.02.2021 | River Plate | - | Danubio | 0:4 | ||||
| 9. Journée | 20.02.2021 | River Plate | - | Cerro Largo | 2:0 | ||||
| 10. Journée | 27.02.2021 | River Plate | - | Montevideo Wanderers | 1:1 | ||||
| 11. Journée | 07.03.2021 | Peñarol | - | River Plate | 2:0 | ||||
| 13. Journée | 20.03.2021 | River Plate | - | Montevideo City Torque | 1:1 |
Uruguay