| 1. Journée | 11.09.2021 | Sud América | - | Montevideo City Torque | 1:2 | ||||
| 2. Journée | 19.09.2021 | Montevideo City Torque | - | Plaza Colonia | 2:2 | ||||
| 4. Journée | 03.10.2021 | Montevideo City Torque | - | Boston River | 4:3 | ||||
| 5. Journée | 09.10.2021 | Montevideo Wanderers | - | Montevideo City Torque | 0:1 | ||||
| 6. Journée | 16.10.2021 | Montevideo City Torque | - | Rentistas | 1:2 | ||||
| 7. Journée | 21.10.2021 | Peñarol | - | Montevideo City Torque | 3:1 | ||||
| 8. Journée | 24.10.2021 | Deportivo Maldonado | - | Montevideo City Torque | 2:1 |  |
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| 9. Journée | 31.10.2021 | Montevideo City Torque | - | Villa Española | 5:0 | ||||
| 10. Journée | 04.11.2021 | Nacional | - | Montevideo City Torque | 2:0 | ||||
| 11. Journée | 07.11.2021 | Cerrito | - | Montevideo City Torque | 0:2 | ||||
| 12. Journée | 13.11.2021 | Liverpool | - | Montevideo City Torque | 1:3 | |
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| 13. Journée | 22.11.2021 | Montevideo City Torque | - | River Plate | 1:1 | ||||
| 14. Journée | 29.11.2021 | Cerro Largo | - | Montevideo City Torque | 1:1 | ||||
| 15. Journée | 04.12.2021 | Montevideo City Torque | - | Progreso | 1:0 |  |
Uruguay