| 2. Journée | 11.09.2021 | sc Heerenveen [U21] | - | NAC Breda [U21] | 0:1 | ||||
| 3. Journée | 18.09.2021 | Almere City FC [U21] | - | sc Heerenveen [U21] | 2:1 | ||||
| 4. Journée | 25.09.2021 | sc Heerenveen [U21] | - | FC Groningen [U21] | 4:2 | ||||
| 6. Journée | 18.10.2021 | Feyenoord [U21] | - | sc Heerenveen [U21] | 2:0 | ||||
| 8. Journée | 30.10.2021 | sc Heerenveen [U21] | - | NEC Nijmegen [U21] | 0:3 | ||||
| 10. Journée | 20.11.2021 | sc Heerenveen [U21] | - | Almere City FC [U21] | 2:4 | ||||
| 14. Journée | 04.02.2022 | sc Heerenveen [U21] | - | Feyenoord [U21] | 2:2 |
Pays-Bas