| 4. Journée | 11.09.2010 | Hamilton Academical | - | Rangers FC | 1:2 |  |
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| 5. Journée | 18.09.2010 | Hibernian FC | - | Hamilton Academical | 1:1 | ||||
| 6. Journée | 25.09.2010 | Hamilton Academical | - | Kilmarnock FC | 2:2 | |
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| 7. Journée | 02.10.2010 | Celtic FC | - | Hamilton Academical | 3:1 | ||||
| 8. Journée | 16.10.2010 | St. Mirren FC | - | Hamilton Academical | 2:2 | ||||
| 9. Journée | 23.10.2010 | Hamilton Academical | - | St. Johnstone FC | 1:2 | ||||
| 10. Journée | 30.10.2010 | Motherwell FC | - | Hamilton Academical | 0:1 | ||||
| 11. Journée | 06.11.2010 | Hamilton Academical | - | Dundee United | 0:1 | ||||
| 12. Journée | 10.11.2010 | Kilmarnock FC | - | Hamilton Academical | 3:0 | |
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| 13. Journée | 13.11.2010 | Hamilton Academical | - | Inverness CT | 1:3 | ||||
| 14. Journée | 20.11.2010 | Heart of Midlothian | - | Hamilton Academical | 2:0 | ||||
| 15. Journée | 27.11.2010 | Hamilton Academical | - | St. Mirren FC | 0:0 | |
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| 20. Journée | 29.12.2010 | Hamilton Academical | - | Aberdeen FC | 0:1 | ||||
| 21. Journée | 01.01.2011 | Hamilton Academical | - | Motherwell FC | 0:0 | |
Irlande