| 1. Journée | 25.06.2022 | Mazatlán FC [] | - | Club Tijuana [] | 0:3 | ||||
| 2. Journée | 02.07.2022 | Club Tijuana [] | - | Santos Laguna [] | 2:0 | ||||
| 3. Journée | 09.07.2022 | Atlas Guadalajara [] | - | Club Tijuana [] | 0:0 | ||||
| 4. Journée | 16.07.2022 | Club Tijuana [] | - | UANL Tigres [] | 8:2 | ||||
| 5. Journée | 23.07.2022 | Club León [] | - | Club Tijuana [] | 0:1 | ||||
| 6. Journée | 31.07.2022 | Club Tijuana [] | - | Deportivo Guadalajara [] | 3:1 | ||||
| 8. Journée | 13.08.2022 | CF Monterrey [] | - | Club Tijuana [] | 3:2 | ||||
| 9. Journée | 20.08.2022 | Club Tijuana [] | - | Atlético San Luis [] | 6:3 |  |
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| 12. Journée | 10.09.2022 | Club Tijuana [] | - | CF Monterrey [] | 2:2 | ||||
| 14. Journée | 25.09.2022 | Deportivo Guadalajara [] | - | Club Tijuana [] | 2:1 | ||||
| 16. Journée | 08.10.2022 | UANL Tigres [] | - | Club Tijuana [] | 1:0 | ||||
| 18. Journée | 22.10.2022 | Santos Laguna [] | - | Club Tijuana [] | 1:0 |
Mexique