| 1. Journée | 22.01.2023 | Lobos UPNFM | - | Motagua | 2:1 |  |
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| 2. Journée | 25.01.2023 | Real Sociedad | - | Lobos UPNFM | 1:1 |  |
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| 3. Journée | 29.01.2023 | Honduras Progreso | - | Lobos UPNFM | 0:2 | ||||
| 4. Journée | 02.02.2023 | Lobos UPNFM | - | Victoria | 1:0 | ||||
| 5. Journée | 05.02.2023 | Olancho FC | - | Lobos UPNFM | 4:1 | |
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| 6. Journée | 12.02.2023 | Lobos UPNFM | - | Marathón | 2:1 | ||||
| 7. Journée | 16.02.2023 | Lobos UPNFM | - | Real España | 1:1 | ||||
| 8. Journée | 19.02.2023 | Olimpia | - | Lobos UPNFM | 4:1 | |
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| 9. Journée | 26.02.2023 | Lobos UPNFM | - | Vida | 3:0 | ||||
| 10. Journée | 02.03.2023 | Motagua | - | Lobos UPNFM | 4:3 | ||||
| 11. Journée | 06.03.2023 | Lobos UPNFM | - | Real Sociedad | 1:1 | ||||
| 12. Journée | 12.03.2023 | Lobos UPNFM | - | Honduras Progreso | 4:2 | |
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| 14. Journée | 02.04.2023 | Lobos UPNFM | - | Olancho FC | 1:0 | |
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| 15. Journée | 06.04.2023 | Marathón | - | Lobos UPNFM | 1:1 | |
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| 16. Journée | 17.04.2023 | Real España | - | Lobos UPNFM | 3:1 | |
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| 17. Journée | 24.04.2023 | Lobos UPNFM | - | Olimpia | 1:2 | ||||
| 18. Journée | 29.04.2023 | Vida | - | Lobos UPNFM | 2:1 |
Honduras