| 1. Journée | 27.09.2020 | Lobos UPNFM | - | Motagua | 2:3 |  |
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| 2. Journée | 07.10.2020 | Real Sociedad | - | Lobos UPNFM | 2:3 | |
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| 13. Journée | 15.11.2020 | Lobos UPNFM | - | Real España | 1:1 | ||||
| 10. Journée | 23.11.2020 | Lobos UPNFM | - | Honduras Progreso | 0:1 | ||||
| 12. Journée | 30.11.2020 | Platense | - | Lobos UPNFM | 1:1 | ||||
| 6. Journée | 06.12.2020 | Motagua | - | Lobos UPNFM | 0:1 | ||||
| 14. Journée | 12.12.2020 | Vida | - | Lobos UPNFM | 0:3 |
Honduras