| 3. Journée | 20.02.2022 | General Caballero DJLM | - | Tacuary | 2:0 | ||||
| 4. Journée | 28.02.2022 | Tacuary | - | Libertad | 0:1 | ||||
| 10. Journée | 19.04.2022 | Sol de América | - | Tacuary | 1:0 | ||||
| 15. Journée | 11.05.2022 | Libertad | - | Tacuary | 3:0 | ||||
| 17. Journée | 20.05.2022 | Tacuary | - | Sportivo Ameliano | 1:0 | ||||
| 18. Journée | 13.06.2022 | Club Nacional | - | Tacuary | 3:0 | ||||
| 19. Journée | 20.06.2022 | Tacuary | - | Guaraní | 0:2 | ||||
| 21. Journée | 28.06.2022 | Tacuary | - | Sol de América | 2:2 |
Paraguay