| 1. Journée | 03.07.2022 | Oriente Petrolero | - | The Strongest | 3:0 | ||||
| 7. Journée | 31.07.2022 | Bolívar | - | The Strongest | 0:4 | ||||
| 8. Journée | 07.08.2022 | The Strongest | - | Universitario de Vinto | 3:2 | ||||
| 9. Journée | 10.08.2022 | Real Santa Cruz | - | The Strongest | 0:3 | ||||
| 10. Journée | 13.08.2022 | The Strongest | - | Atlético Palmaflor | 1:1 |  |
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| 14. Journée | 31.08.2022 | The Strongest | - | CD Guabirá | 2:3 | |
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| 16. Journée | 09.09.2022 | The Strongest | - | Oriente Petrolero | 2:1 | |
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| 17. Journée | 11.09.2022 | Jorge Wilstermann | - | The Strongest | 0:3 | ||||
| 19. Journée | 02.10.2022 | The Strongest | - | Universitario de Sucre | 1:0 | ||||
| 20. Journée | 06.10.2022 | Club Aurora | - | The Strongest | 0:0 | ||||
| 21. Journée | 08.10.2022 | Always Ready | - | The Strongest | 1:3 | ||||
| 22. Journée | 13.10.2022 | The Strongest | - | Bolívar | 4:4 |  |
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Paraguay