| 1. Journée | 12.09.2021 | KS Kastrioti | - | Dinamo Tiranë | 0:2 | ||||
| 2. Journée | 19.09.2021 | FK Kukësi | - | KS Kastrioti | 3:1 | ||||
| 3. Journée | 25.09.2021 | KS Kastrioti | - | KF Tiranë | 1:1 | ||||
| 4. Journée | 02.10.2021 | Egnatia Rrogozhine | - | KS Kastrioti | 2:1 |  |
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| 5. Journée | 16.10.2021 | KS Kastrioti | - | KF Skënderbeu | 2:0 | ||||
| 6. Journée | 23.10.2021 | KS Kastrioti | - | KF Laçi | 0:1 | ||||
| 7. Journée | 31.10.2021 | KF Teuta Durrës | - | KS Kastrioti | 1:1 | ||||
| 8. Journée | 07.11.2021 | KS Kastrioti | - | FK Partizani | 0:2 | ||||
| 9. Journée | 20.11.2021 | FK Vllaznia | - | KS Kastrioti | 3:1 | |
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| 10. Journée | 28.11.2021 | Dinamo Tiranë | - | KS Kastrioti | 1:0 | |
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| 11. Journée | 04.12.2021 | KS Kastrioti | - | FK Kukësi | 1:6 | ||||
| 12. Journée | 07.12.2021 | KF Tiranë | - | KS Kastrioti | 3:0 | ||||
| 13. Journée | 12.12.2021 | KS Kastrioti | - | Egnatia Rrogozhine | 1:0 | ||||
| 14. Journée | 18.12.2021 | KF Skënderbeu | - | KS Kastrioti | 2:1 | ||||
| 15. Journée | 22.12.2021 | KF Laçi | - | KS Kastrioti | 2:0 | ||||
| 16. Journée | 16.01.2022 | KS Kastrioti | - | KF Teuta Durrës | 2:0 | |
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| 18. Journée | 30.01.2022 | KS Kastrioti | - | FK Vllaznia | 0:1 | |
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