| 2. Journée | 24.02.2019 | Defensor Sporting | - | Cerro Largo | 0:3 | ||||
| 4. Journée | 09.03.2019 | Defensor Sporting | - | Juventud de Las Piedras | 1:4 | ||||
| 5. Journée | 16.03.2019 | Liverpool | - | Defensor Sporting | 6:2 | ||||
| 7. Journée | 31.03.2019 | Racing | - | Defensor Sporting | 4:2 | ||||
| 8. Journée | 07.04.2019 | Defensor Sporting | - | Boston River | 0:0 | ||||
| 10. Journée | 21.04.2019 | Defensor Sporting | - | Plaza Colonia | 4:1 |  |
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| 11. Journée | 05.05.2019 | CA Cerro | - | Defensor Sporting | 0:2 | ||||
| 12. Journée | 11.05.2019 | Defensor Sporting | - | River Plate | 1:1 | ||||
| 13. Journée | 19.05.2019 | Nacional | - | Defensor Sporting | 1:0 | ||||
| 14. Journée | 25.05.2019 | Defensor Sporting | - | Fénix | 2:4 | ||||
| 15. Journée | 01.06.2019 | Progreso | - | Defensor Sporting | 0:3 |
Uruguay