| Groupe A | 05.11.2020 | AS Roma | - | CFR Cluj | 5:0 |  |
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| Groupe A | 03.12.2020 | AS Roma | - | BSC Young Boys | 3:1 | ||||
| Seizièmes de finale | 18.02.2021 | Sporting Braga | - | AS Roma | 0:2 | ||||
| tour des 16 | 11.03.2021 | AS Roma | - | Shakhtar Donetsk | 3:0 | ||||
| tour des 16 | 18.03.2021 | Shakhtar Donetsk | - | AS Roma | 1:2 |  |
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| Quarts de finale | 08.04.2021 | AFC Ajax | - | AS Roma | 1:2 | |
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| Quarts de finale | 15.04.2021 | AS Roma | - | AFC Ajax | 1:1 | |
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| Demi-finales | 29.04.2021 | Manchester United | - | AS Roma | 6:2 | ||||
| Demi-finales | 06.05.2021 | AS Roma | - | Manchester United | 3:2 |
Brésil
Uruguay 
