| 1. Journée | 03.02.2018 | River Plate | - | Boston River | 2:2 | ||||
| 2. Journée | 10.02.2018 | Boston River | - | Montevideo Wanderers | 1:3 | ||||
| 3. Journée | 17.02.2018 | Liverpool | - | Boston River | 2:2 |  |
|||
| 5. Journée | 03.03.2018 | CA Cerro | - | Boston River | 2:3 |  |
|||
| 6. Journée | 10.03.2018 | Peñarol | - | Boston River | 2:1 | |
|||
| 7. Journée | 21.03.2018 | Boston River | - | Atenas | 1:0 | ||||
| 8. Journée | 24.03.2018 | Danubio | - | Boston River | 0:0 | ||||
| 9. Journée | 28.03.2018 | Boston River | - | Torque | 1:1 | ||||
| 11. Journée | 06.04.2018 | Boston River | - | Fénix | 0:3 | ||||
| 15. Journée | 06.05.2018 | Boston River | - | Racing | 2:1 |
Uruguay