| 1. Journée | 31.08.2016 | Boston River | - | Defensor Sporting | 1:1 | ||||
| 2. Journée | 04.09.2016 | Defensor Sporting | - | Juventud de Las Piedras | 0:1 |  |
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| 3. Journée | 11.09.2016 | Defensor Sporting | - | Sud América | 2:0 | ||||
| 4. Journée | 18.09.2016 | River Plate | - | Defensor Sporting | 0:5 |  |
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| 5. Journée | 24.09.2016 | Defensor Sporting | - | CA Cerro | 0:1 | ||||
| 6. Journée | 02.10.2016 | Defensor Sporting | - | Montevideo Wanderers | 1:1 | ||||
| 7. Journée | 09.10.2016 | Fénix | - | Defensor Sporting | 3:1 | ||||
| 8. Journée | 16.10.2016 | Defensor Sporting | - | Liverpool | 1:3 | ||||
| 12. Journée | 20.11.2016 | Defensor Sporting | - | Nacional | 3:2 | ||||
| 13. Journée | 26.11.2016 | Defensor Sporting | - | Danubio | 0:0 | ||||
| 15. Journée | 10.12.2016 | Peñarol | - | Defensor Sporting | 0:2 | |
Uruguay
Portugal