| 1. Journée | 16.02.2019 | Montevideo Wanderers | - | River Plate | 1:1 | ||||
| 2. Journée | 23.02.2019 | River Plate | - | Racing | 4:1 | ||||
| 3. Journée | 03.03.2019 | Boston River | - | River Plate | 2:0 | ||||
| 4. Journée | 10.03.2019 | River Plate | - | Danubio | 1:1 | ||||
| 5. Journée | 17.03.2019 | Plaza Colonia | - | River Plate | 1:0 | ||||
| 6. Journée | 24.03.2019 | River Plate | - | CA Cerro | 2:1 | ||||
| 7. Journée | 30.03.2019 | Cerro Largo | - | River Plate | 2:0 | ||||
| 8. Journée | 06.04.2019 | Nacional | - | River Plate | 6:0 | ||||
| 9. Journée | 14.04.2019 | River Plate | - | Fénix | 2:2 |  |
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| 10. Journée | 20.04.2019 | Progreso | - | River Plate | 4:0 | ||||
| 11. Journée | 04.05.2019 | River Plate | - | Peñarol | 0:2 | ||||
| 12. Journée | 11.05.2019 | Defensor Sporting | - | River Plate | 1:1 | ||||
| 13. Journée | 18.05.2019 | River Plate | - | Rampla Juniors | 2:1 | ||||
| 15. Journée | 02.06.2019 | River Plate | - | Liverpool | 0:0 |
Uruguay