| Zona B | 06.03.2021 | Cobán Imperial | - | Sanarate | 2:0 | ||||
| Zona B | 31.03.2021 | Cobán Imperial | - | Achuapa | 3:2 | ||||
| Zona B | 10.04.2021 | Cobán Imperial | - | Deportivo Guastatoya | 0:1 | ||||
| Demi-finales Groupe A | 14.04.2021 | Cobán Imperial | - | Iztapa | 2:2 | ||||
| Demi-finales Groupe A | 21.04.2021 | Cobán Imperial | - | Xelaju MC | 0:0 | ||||
| Quarts de finale | 09.05.2021 | Santa Lucía | - | Cobán Imperial | 3:0 |  |
Guatemala