| 4. Journée | 19.06.2022 | Rio Grande Valley FC | - | Pittsburgh Riverhounds | 1:0 | ||||
| 4. Journée | 30.06.2022 | Rio Grande Valley FC | - | El Paso Locomotive | 0:0 | ||||
| 5. Journée | 07.07.2022 | New Mexico United | - | Rio Grande Valley FC | 1:0 | ||||
| 5. Journée | 10.07.2022 | New Mexico United | - | Rio Grande Valley FC | 1:1 | ||||
| 5. Journée | 18.07.2022 | Rio Grande Valley FC | - | Las Vegas Lights FC | 0:1 | ||||
| 5. Journée | 24.07.2022 | San Diego Loyal | - | Rio Grande Valley FC | 2:1 | ||||
| 5. Journée | 28.07.2022 | Rio Grande Valley FC | - | Hartford Athletic | 0:0 | ||||
| 7. Journée | 24.09.2022 | Charleston Battery | - | Rio Grande Valley FC | 0:3 | ||||
| 8. Journée | 02.10.2022 | Rio Grande Valley FC | - | Louisville City FC | 0:1 | ||||
| 8. Journée | 06.10.2022 | Memphis 901 | - | Rio Grande Valley FC | 2:2 |
Colombie