| 1. Journée | 17.02.2022 | Deportes Melipilla | - | Universidad de Concepción | 0:2 | ||||
| 2. Journée | 24.02.2022 | Rangers | - | Deportes Melipilla | 1:0 | ||||
| 3. Journée | 02.03.2022 | Deportes Melipilla | - | Puerto Montt | 1:1 | ||||
| 11. Journée | 26.04.2022 | Deportes Temuco | - | Deportes Melipilla | 1:1 |  |
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| 12. Journée | 30.04.2022 | Deportes Melipilla | - | Barnechea | 2:1 | ||||
| 13. Journée | 08.05.2022 | Fernández Vial | - | Deportes Melipilla | 1:1 | ||||
| 14. Journée | 13.05.2022 | Deportes Melipilla | - | CD Magallanes | 1:2 | ||||
| 23. Journée | 10.08.2022 | Deportes Melipilla | - | Unión San Felipe | 1:0 | ||||
| 25. Journée | 25.08.2022 | Cobreloa | - | Deportes Melipilla | 1:0 | ||||
| 32. Journée | 18.10.2022 | Deportes Melipilla | - | Santiago Morning | 2:1 | ||||
| 33. Journée | 24.10.2022 | Santa Cruz | - | Deportes Melipilla | 2:1 | ||||
| 34. Journée | 01.11.2022 | Deportes Melipilla | - | Deportes Iquique | 0:0 |
Chili