| 8. Journée | 09.04.2022 | Deportes Melipilla | - | Cobreloa | 0:0 |  |
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| 11. Journée | 26.04.2022 | Deportes Temuco | - | Deportes Melipilla | 1:1 | ||||
| 13. Journée | 08.05.2022 | Fernández Vial | - | Deportes Melipilla | 1:1 |  |
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| 14. Journée | 13.05.2022 | Deportes Melipilla | - | CD Magallanes | 1:2 | ||||
| 15. Journée | 16.05.2022 | Santiago Morning | - | Deportes Melipilla | 1:1 | |
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| 16. Journée | 22.05.2022 | Deportes Melipilla | - | Santa Cruz | 1:0 | |
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| 17. Journée | 29.05.2022 | Deportes Iquique | - | Deportes Melipilla | 3:0 | ||||
| 18. Journée | 05.07.2022 | Universidad de Concepción | - | Deportes Melipilla | 1:1 | ||||
| 28. Journée | 13.09.2022 | Deportes Melipilla | - | Deportes Temuco | 0:1 | ||||
| 31. Journée | 09.10.2022 | CD Magallanes | - | Deportes Melipilla | 7:0 | |
Chili