| 2. Journée | 12.03.2022 | Inter Miami CF | - | Los Angeles FC | 0:2 | ||||
| 2. Journée | 21.03.2022 | Los Angeles FC | - | Vancouver Whitecaps | 3:1 | ||||
| 3. Journée | 03.04.2022 | Orlando City | - | Los Angeles FC | 2:4 |  |
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| 3. Journée | 17.04.2022 | Los Angeles FC | - | Sporting Kansas City | 3:1 | ||||
| 4. Journée | 02.05.2022 | Los Angeles FC | - | Minnesota United FC | 2:0 | ||||
| 4. Journée | 08.05.2022 | Los Angeles FC | - | Philadelphia Union | 2:2 | ||||
| 4. Journée | 14.05.2022 | Colorado Rapids | - | Los Angeles FC | 2:0 | ||||
| 4. Journée | 19.05.2022 | Los Angeles FC | - | Austin FC | 1:2 | ||||
| 4. Journée | 21.05.2022 | Columbus Crew | - | Los Angeles FC | 0:2 | ||||
| 4. Journée | 29.05.2022 | Los Angeles FC | - | San Jose Earthquakes | 3:2 | ||||
| 5. Journée | 18.06.2022 | Seattle Sounders | - | Los Angeles FC | 1:1 | ||||
| 5. Journée | 26.06.2022 | Los Angeles FC | - | New York RB | 2:0 | ||||
| 5. Journée | 30.06.2022 | Los Angeles FC | - | FC Dallas | 3:1 | ||||
| 6. Journée | 03.07.2022 | Vancouver Whitecaps | - | Los Angeles FC | 1:0 | ||||
| 6. Journée | 09.07.2022 | Los Angeles FC | - | Los Angeles Galaxy | 3:2 |
Uruguay
Italie