| 2. Journée | 21.08.2020 | Hrvatski Dragovoljac | - | NK Osijek II | 2:1 | ||||
| 3. Journée | 23.09.2020 | NK Osijek II | - | NK Croatia Zmijavci | 0:1 | ||||
| 7. Journée | 26.09.2020 | NK Inter Zaprešić | - | NK Osijek II | 0:1 | ||||
| 8. Journée | 30.09.2020 | NK Osijek II | - | NK Kustošija | 1:0 | ||||
| 18. Journée | 13.02.2021 | HNK Orijent Rijeka | - | NK Osijek II | 3:0 | ||||
| 19. Journée | 22.02.2021 | NK Osijek II | - | Hrvatski Dragovoljac | 0:0 | ||||
| 20. Journée | 28.02.2021 | NK Croatia Zmijavci | - | NK Osijek II | 1:0 | ||||
| 23. Journée | 19.03.2021 | NK Međimurje | - | NK Osijek II | 0:1 | ||||
| 24. Journée | 02.04.2021 | NK Osijek II | - | NK Inter Zaprešić | 1:2 | ||||
| 25. Journée | 10.04.2021 | NK Kustošija | - | NK Osijek II | 1:0 | ||||
| 26. Journée | 17.04.2021 | NK Osijek II | - | NK Opatija | 1:0 | ||||
| 28. Journée | 24.04.2021 | NK Osijek II | - | NK BSK Bijelo Brdo | 3:0 | ||||
| 27. Journée | 28.04.2021 | Dinamo Zagreb II | - | NK Osijek II | 3:0 | ||||
| 29. Journée | 02.05.2021 | Hajduk Split II | - | NK Osijek II | 4:3 |  |
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| 30. Journée | 08.05.2021 | NK Osijek II | - | NK Sesvete | 0:3 | |
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| 32. Journée | 16.05.2021 | NK Osijek II | - | NK Rudeš | 2:3 | ||||
| 34. Journée | 29.05.2021 | NK Osijek II | - | NK Dubrava | 0:5 |
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