| 3. Journée | 11.09.2016 | Juventud de Las Piedras | - | River Plate | 0:0 | ||||
| 4. Journée | 18.09.2016 | River Plate | - | Defensor Sporting | 0:5 | ||||
| 7. Journée | 08.10.2016 | Liverpool | - | River Plate | 2:2 |  |
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| 8. Journée | 16.10.2016 | River Plate | - | Plaza Colonia | 2:1 | |
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| 9. Journée | 23.10.2016 | Danubio | - | River Plate | 2:1 | |
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| 10. Journée | 30.10.2016 | Nacional | - | River Plate | 3:1 | ||||
| 11. Journée | 13.11.2016 | Rampla Juniors | - | River Plate | 0:2 | ||||
| 12. Journée | 19.11.2016 | Racing | - | River Plate | 2:1 | ||||
| 13. Journée | 26.11.2016 | River Plate | - | Villa Española | 2:1 |
Uruguay