| 1. Journée | 01.08.2021 | Luis Ángel Firpo | - | Jocoro FC | 1:1 | ||||
| 2. Journée | 08.08.2021 | Municipal Limeño | - | Luis Ángel Firpo | 1:1 | ||||
| 3. Journée | 11.08.2021 | Luis Ángel Firpo | - | Platense Zacatecoluca | 3:2 |  |
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| 4. Journée | 15.08.2021 | Alianza | - | Luis Ángel Firpo | 2:2 | |
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| 6. Journée | 25.08.2021 | Luis Ángel Firpo | - | Once Municipal | 2:2 | ||||
| 8. Journée | 12.09.2021 | Luis Ángel Firpo | - | Isidro Metapán | 1:1 | ||||
| 9. Journée | 15.09.2021 | Atlético Marte | - | Luis Ángel Firpo | 1:3 | ||||
| 10. Journée | 19.09.2021 | Luis Ángel Firpo | - | Santa Tecla FC | 0:0 | ||||
| 12. Journée | 02.10.2021 | Jocoro FC | - | Luis Ángel Firpo | 2:1 | ||||
| 15. Journée | 24.10.2021 | Luis Ángel Firpo | - | Alianza | 2:1 | ||||
| 16. Journée | 31.10.2021 | Luis Ángel Firpo | - | AD Chalatenango | 4:2 | ||||
| 17. Journée | 02.11.2021 | Once Municipal | - | Luis Ángel Firpo | 1:0 | ||||
| 21. Journée | 21.11.2021 | Santa Tecla FC | - | Luis Ángel Firpo | 2:2 | ||||
| 22. Journée | 27.11.2021 | Luis Ángel Firpo | - | CD Águila | 1:0 |
El Salvador