| 4. Journée | 03.06.2018 | Columbus Crew | - | Toronto FC | 3:3 | ||||
| 4. Journée | 09.06.2018 | Columbus Crew | - | New York RB | 1:1 | ||||
| 4. Journée | 14.06.2018 | Columbus Crew | - | Atlanta United FC | 0:2 | ||||
| 4. Journée | 24.06.2018 | Los Angeles FC | - | Columbus Crew | 2:0 | ||||
| 5. Journée | 01.07.2018 | Columbus Crew | - | Real Salt Lake | 2:1 |  |
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| 5. Journée | 08.07.2018 | Los Angeles Galaxy | - | Columbus Crew | 4:0 | ||||
| 5. Journée | 15.07.2018 | New York City FC | - | Columbus Crew | 2:0 |  |
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| 7. Journée | 20.09.2018 | Portland Timbers | - | Columbus Crew | 3:2 | ||||
| 7. Journée | 23.09.2018 | Columbus Crew | - | Colorado Rapids | 2:1 | ||||
| 7. Journée | 30.09.2018 | Columbus Crew | - | Philadelphia Union | 0:0 |
Venezuela